NIH Pub. Other conditions unrelated to breast cancer may cause a breast rash, including infection, allergic reaction, or shingles. Can diet help improve depression symptoms? Because the hormones in your body are constantly changing, so are your breasts. Become a volunteer, make a tax-deductible donation, or participate in a fundraising event to help us save lives. If the pathology results show that the skin and dermal lymphatics of the breast skin contain breast cancer cells, this confirms it is inflammatory breast cancer. According to the American Cancer Society, inflammatory breast cancer (IBC) accounts for roughly 1 to 5 percent of all breast cancer diagnoses. Underuse of trimodality treatment affects survival for patients with inflammatory breast cancer: an analysis of treatment and survival trends from the National Cancer Database. Adjuvant therapy: Adjuvant systemic therapy may be given after surgery to reduce the chance of cancer recurrence. Inflammatory breast cancer causes visible changes in the skin of the breast. 6th ed. The sooner treatment starts, the better the chances are of recovery. In addition, the skin may have ridges or appear pitted, like the skin of an orange (called peau d'orange). If you have a breast rash, speak with your healthcare provider so they can run diagnostic tests to determine the cause and treat the underlying condition. Inflammatory Breast Cancer rash is a very aggressive subtype of breast cancer. Yamauchi H, Ueno NT. If you have mastitis, your symptoms may come on without warning. National Cancer Institute It is important, therefore, that women who are diagnosed with inflammatory breast cancer talk with their doctor about the option of participating in a clinical trial. Cancer.org is provided courtesy of the Leo and Gloria Rosen family. In about 1 of every 3 cases, IBC has already spread (metastasized) to distant parts of the body when it is diagnosed. 1. They cant tell you how long you will live, but they may help give you a better understanding of how likely it is that your treatment will be successful. We also attend research meetings, serve on grant committee's, advocate, educate and run online support groups, just to list a few ways we spend our time. Other conditions unrelated to breast cancer may cause a breast rash, including infection, allergic reaction, or shingles. Waltham, Mass. Inflammatory breast cancer is uncommon, accounting for .5% to 2% of all breast cancers. Eur J Surg Oncol. Inflammatory breast cancer (IBC) is a rare, aggressive breast cancer that develops when cancer cells get into the lymph vessels in the skin of your breast. Cancer cells that make too much of a protein called HER2 or too many copies of the gene for that protein may be treated by certain drugs that target HER2. Cookies are small text files that can be used by websites to make a user's experience more efficient. Self-examination and noticing breast changes can play a critical role in the timely detection of breast cancer. Inflammatory breast cancer develops when cancer cells block the lymph vessels in the skin of the breast. Verywell Health's content is for informational and educational purposes only. A breast abscess is a sign of a bacterial infection. The intention is to display ads that are relevant and engaging for the individual user and thereby more valuable for publishers and third party advertisers. There often isnt a lump, making IBC challenging to diagnose. : UpToDate, 2021. https://www.uptodate.com. That diagnosis changed her entire outlook, and today she's making it her mission to educate others and raise awareness for the deadly disease. Symptoms of shingles include: Breast cancer symptoms vary by the individual; some people are asymptomatic and present few or no symptoms initially. About two days ago, I notice a small itchy rash near my armpit. There may be no lump, and cancer may not show up on a mammogram. A skin rash on your breast could be a sign of an aggressive form of breast cancer known as inflammatory breast cancer (IBC). The prognosis, or likely outcome, for a patient diagnosed with cancer is often viewed as the chance that the cancer will be treated successfully and that the patient will recover completely. We know how quickly patients want results from a biopsy if there is a suspicion of breast cancer, so pathologic analysis proceeds very quickly. If you notice any changes during a breast self-exam, notify your healthcare provider. Pagets disease is a rare skin disorder thats often linked to breast cancer in the tissues behind your nipple. The Women's Cancer Program at Mayo Clinic researches new treatment . Exposure to an allergen can cause hives that may affect the chest and breasts. A cancer that develops in the breast cells and progresses in stages. Rashes are not a common symptom of cancer. Surg Clin North Am. SEER Cancer Statistics Review, 1975-2017, National Cancer Institute. One of the first signs is most likely to be visible swelling (edema) of the skin of the breast and/or redness of the breast (covers more than 30 percent of the breast). Inflammatory breast cancer is a rare subtype of locally advanced primary breast cancer, accounting for roughly 2.5% of breast cancers in the United States. Many factors can influence a cancer patients prognosis, including the type and location of the cancer, the stage of the disease, the patients age and overall general health, and the extent to which the patients disease responds to treatment. Many women dont feel a lump. IBC tends to occur in younger women (younger than 40 years of age). Symptoms may include: Mastitis, or inflammation of the breast, is often due to an infection. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Centers for Disease Control and Prevention (CDC), https://www.ncbi.nlm.nih.gov/books/NBK557782/, https://www.cancer.org/cancer/breast-cancer/non-cancerous-breast-conditions/duct-ectasia.html, https://link.springer.com/article/10.1007%2Fs13244-016-0499-0, https://www.ncbi.nlm.nih.gov/books/NBK557665/, https://www.cancer.gov/types/breast/ibc-fact-sheet, https://www.cancer.org/cancer/breast-cancer/understanding-a-breast-cancer-diagnosis/types-of-breast-cancer/inflammatory-breast-cancer.html, https://www.cancer.gov/types/breast/paget-breast-fact-sheet, http://www.breastcancer.org/treatment/side_effects/rash, https://www.cdc.gov/breastfeeding/breastfeeding-special-circumstances/maternal-or-infant-illnesses/shingles.html, https://www.ncbi.nlm.nih.gov/books/NBK459122/, https://www.ruh.nhs.uk/patients/patient_information/BRU030_Intertrigo.pdf, Skipping breakfast and fasting may compromise the immune system. National Comprehensive Cancer Network (NCCN). Sometimes the breast may contain a solid tumor that can be felt during a physical exam, but more often a tumor cannot be felt. What does inflammatory breast cancer rash look like? Inflammatory Breast Cancer (IBC): IBC is a rare form of breast cancer that can cause the skin to become red, swollen, and pitted. With aggressive treatment, the survival rate for inflammatory breast cancer patients has improved significantly in recent years. I now know I need to stay in tune with my body because that small rash became a death sentence." "I felt fine. Risk factors may include: Breast cancer screening refers to checking a womans breast for cancer before there are any signs or symptoms. You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. Naoto Tada Ueno, MD, PhD, FACP, discusses the diagnosis and treatment of patients with inflammatory breast cancer and highlights the biggest challenges in both diagnosing and treating this patient . The epidemiology, clinical features, treatment, and prognosis of IBC will be reviewed here. It blocks the lymph vessels in the skin of your. (Medical Images) Inflammatory breast cancer (IBC) is an aggressive, fast-growing type of breast cancer. You may notice a burning feeling if youre nursing. Unfortunately, inflammatory breast cancer symptoms will not resolve on their own without treatment or intervention, so its important to see a doctor immediately if you have any of the symptoms mentioned above. Is there a link between oral contraceptives and breast cancer? Inflammatory breast tumors are frequently. Lactational mastitis occurs during breastfeeding and is the most common type of mastitis. This surgery involves removal of the entire affected breast and most or all of the lymph nodes under the adjacent arm. The skin also may appear ridged or pitted, which is called peau d'orange . A breast rash can indicate inflammatory breast cancer (IBC), a rare, aggressive cancer that often goes undetected. Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. According to the Centers for Disease Control and Prevention (CDC), shingles cannot pass from one person to another, and a person cannot pass it on through breast milk. Most oncologists recommend both local treatment of the affected breast and systemic treatment (whole body treatment). Try to fully empty your breasts so youre less likely to get an abscess -- a pocket of pus that may need draining. Menta A, Fouad TM, Lucci A, Le-Petross H, Stauder MC, Woodward WA, Ueno NT, Lim B. Many of these symptoms develop quickly, usually within a period of 3 to 6 months. (2017). 2005-2023 Healthline Media a Red Ventures Company. The skin might take on a pink hue or appear swollen and dimpled, with an orange peel appearance. It often produces no distincttumoror lump that can be felt and isolated within the breast. Before starting any treatment, a person should talk with a doctor about possible side effects, including breast rashes. Swelling (edema) of the skin of the breast, Redness involving more than one-third of the breast, Pitting or thickening of the skin of the breast so that it may look and feel like an orange peel, One breast looking larger than the other because of swelling, One breast feeling warmer and heavier than the other, A breast that may be tender, painful or itchy, Swelling of the lymph nodes under the arms or near the collarbone. It presents as an acute onset of an inflamed, erythematous skin. On lighter skin, the rash is typically red in color and has fluid-filled blisters. To help prevent delays in diagnosis and in choosing the best course of treatment, an international panel of experts published guidelines on how doctors can diagnose and stage inflammatory breast cancer correctly. Cancer. Inflammatory breast cancer treatment options may include breast cancer surgery, chemotherapy, radiation therapy, hormone therapy, targeted therapy and immunotherapy. Shingles under the breast can be painful and itchy. Intertrigo is a type of bacterial or fungal infection that occurs in skin folds and can cause under-breast soreness. Below are some of the resources we provide. It often has no symptoms but can cause: Often no treatment is necessary, but a doctor may prescribe antibiotics if an infection is present. It is important to see your gynecologist or primary care physician right away if you have any of these changes in the breast. Philadelphia: Lippincott Williams and Wilkins, 2004. Infected breast tissue, also called mastitis, is most common in women who are nursing. Inflammatory breast cancer is aggressive and fast-growing breast cancer in which cancer cells infiltrate the skin and lymph vessels of the breast. Awareness of how your breasts look and feel can help you catch any symptoms or changes. (2020). The erythema covers at least a third of the breast. Inflammatory breast cancer symptoms result from a buildup of fluid in your breast. The pathology and molecular pathogenesis of IBC are presented separately. For this reason, a person should seek medical advice for any persistent rash on the breast. Hance KW, Anderson WF, Devesa SS, Young HA, Levine PH. Breast infection and inflammatory breast cancer. If you would like to reproduce some or all of this content, see Reuse of NCI Information for guidance about copyright and permissions. small ridges or indents that look like orange peel, a feeling of warmth or heaviness in one breast, itching or tingling of the nipple or areola, skin changes on or around the nipple, such as inflammation, crusting, flaking, or thickening, surgery to remove the breast and possibly lymph nodes, surgery to remove the nipple and areola only. A rash may not necessarily indicate breast cancer, but it's crucial to see a healthcare provider who can determine the cause. It is called inflammatory because the breast becomes red and swollen. Learn about breast cancer rashes, including causes, risk factors, when to see your healthcare provider, and more. This type of breast cancer is aggressive. Inflammatory breast cancer (IBC) is a rare and often aggressive form of invasive breast cancer. Inflammatory breast cancer progresses rapidly, often in a matter of weeks or months. Can physical activity reduce the risk of breast cancer? Breast Lumps: A lump in the breast can be a sign . However, they can sometimes be an early sign of inflammatory breast cancer or. The American Cancer Society medical and editorial content team. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Overmeyer B and Pierce LJ. Kalra MG, Higgins KE, Kinney BS. Diseases of the Breast. Paget's breast disease is another rare cancer-related condition that can cause a rash. But when the lymph vessels become blocked by the breast cancer cells, symptoms begin to appear. Ask to see a specialist (like a breast surgeon) if youre concerned. Because it presents with symptoms similar to that of a breast infection, IBC can be challenging to diagnose. Uncovering the molecular secrets of inflammatory breast cancer biology: an integrated analysis of three distinct affymetrix gene expression datasets. Why might these symptoms seem to come and go? Inflammatory breast cancer is a rare and very aggressive disease in which cancer cells block lymph vessels in the skin of the breast. Inflammatory Breast Cancer, New Techniques to Improve the Survial Rate of Advance Breast Cancer Patients, Breast Cancer Treatment: Weighing the Hormonal Options, What You Need to Know About Breast Cancer Treatment, A red patch of skin, often in a wedge shape, Swelling and redness that affect at least a third of your breast, Skin that looks ridged or pitted like an orange peel, Breast tenderness or a heavy feeling. Bethesda, MD: NCI SEER Program; 2007. That means whether a person's breast cancer is HER2-positive or triple-negative (terms that tell us what therapy they might respond best to), it can present with an inflammatory rash. I'm 27 years old and 35 weeks pregnant with my 3rd child. A tender area or rash on your breast often signals a common problem like an infection. However, these symptoms will become consistently worse as the disease progresses. Common symptoms of IBC include: Orange-peel appearance: Your breast may swell and start to look like the peel of a navel orange (this is called "peau d'orange"). Learn more about the risk factors, symptoms, and treatments for male breast cancer here. These include: Discolored, thickened skin. According to the National Cancer Institute, it occurs in 14% of all breast cancer cases. The skin of the breast may also appear pink, reddish purple, or bruised. Inflammatory breast cancer (IBC) is rare and accounts for only 1% to 5% of all breast cancers. In most cases, a breast rash is not a sign of breast cancer. Jennifer Cordts noticed a red rash on her left breast in 2015. However, since IBC is aggressive, early diagnosis and treatment are important. Breast Cancer Res Treat. Warning signs may include a lump, thickening or swelling of the skin, irritation, discharge, changes in breast size or shape, and pain in the nipple, breast, or underarm area. Inflammatory Breast Cancer Pictures and Symptoms The symptoms of IBC include a breast that: Quickly changes appearance Looks larger, thicker or heavier Feels very warm Has skin that looks dimpled or ridged like an orange Is tender, aches or feels painful Has larger lymph nodes under the arm or around the collarbone It can lead to a rash around one or both of your nipples. How to Spot and Treat a Breast Cancer Rash. Your nipple turns inward or gets flat. IBC symptoms tend to be more prominent and severe than those of noninflammatory breast cancers. If you have any of the symptoms mentioned above or have noticed any abnormal changes to your breasts, consult with a doctor as soon as possible. Whether you want to learn about treatment options, get advice on coping with side effects, or have questions about health insurance, were here to help. Annals of Oncology 2014; 25(2):358-365. The cancer cells in the biopsy will be examined in the lab to determine their grade. Redness of the breast skin (usually affecting more than a third of the breast tissue) Nipple swelling. This spread can cause swollen lymph nodes under your arm or above your collar bone. Some forms of breast cancer medication, chemotherapy, hormone therapy, and radiation can cause rashes, but they are unlikely to affect only the breast. It can also affect women who arent breastfeeding as well as men. A rash under breast caused would also be as a result of scabies, eczema or shingles. Yamauchi H, Woodward WA, Valero V, et al. Annals of Oncology 2014; 25(2):384-91. 2006;106:10001006. Oncology (Williston Park) 2011; 25(3):264-270, 273. Disease-free and overall survival after pathologic complete disease remission of cytologically proven inflammatory breast carcinoma axillary lymph node metastases after primary systemic chemotherapy. Robertson FM, Bondy M, Yang W, et al. Centers for Disease Control and Prevention. This fluid buildup occurs because cancer cells have blocked lymph vessels in the skin, preventing the normal flow of lymph through the tissue. A breast exam includes checking for lumps and abnormalities in the breast and armpits. Generally, an inflammatory breast cancer rash looks like an insect bite. SEER Survival Monograph: Cancer Survival Among Adults: U.S. SEER Program, 1988-2001, Patient and Tumor Characteristics. Signs of inflammatory breast cancer can develop quickly and may include: the breast looks red or inflamed or develops a rash - it often looks as if it's infected or bruised the breast becomes swollen and enlarged and may feel heavy or uncomfortable the breast feels warm and tender In: DeVita VT, Lawrence TS, Lawrence TS, Rosenberg SA, eds. [Cited 2021 September 27]. DeVita, Hellman, and Rosenbergs Cancer: Principles and Practice of Oncology. No. Nipple eczema often affects women about 5 to 6 months after giving birth. Dermatitis is an umbrella term for a handful of inflammatory skin conditions that cause symptoms such as redness, itching, peeling, and more. By continuing, you agree to the terms of our Privacy & Cookies Policies. Bertucci F, Ueno NT, Finetti P, et al. But when the lymph vessels become blocked by the breast cancer cells,symptomsbegin to appear. How often should I do a breast self exam (BSE)? Make sure you finish all your medicine, even if you start feeling better right away. Paget's breast disease is another rare cancer-related condition that can cause a rash. Surveillance Research Program, National Cancer Institute. A doctor will advise people on the most suitable treatment plan. Bethesda, MD, https://seer.cancer.gov/csr/1975_2017/, based on November 2019 SEER data submission, posted to the SEER web site, April 2020. If your primary care physician or gynecologist says it is mastitis, but symptoms persist after a one week treatment of antibiotics, its important to be seen by a breast specialist. UpToDate. Inflammatory breast cancer (IBC) causes a number of signs and symptoms, most of which develop quickly (within 3-6 months), including: Swelling (edema) of the skin of the breast Redness involving more than one-third of the breast Pitting or thickening of the skin of the breast so that it may look and feel like an orange peel Morrow RJ, et al. Philadelphia, Pa: Lippincott-Williams & Wilkins; 2014. Symptoms of inflammatory breast cancer usually develop quickly, often over a few weeks or months. Inflammatory breast cancer: what we know and what we need to learn. Shingles (herpes zoster). Inflammatory breast cancer is aggressive and fast-growing breast cancer in which cancer cells infiltrate the skin and lymph vessels of the breast. Other causes of a rash include an allergy or infection. Masuda H, Brewer TM, Liu DD, et al. It causes symptoms similar to a breast infection. Rashes can signify many different conditions. 1 It is characterized by the disruption . However, because they can be a sign of cancer, it is best to seek medical advice if a rash or skin change occurs on the breast. You could also have discharge or bleeding from your nipple. This makes it harder to diagnose. Pagets disease of the breast is a type of cancer that affects the skin on the nipple and usually the skin around the nipple, known as the areola. Where can I find a breast cancer support group? About Breast Cancer > Types of Breast Cancer > Inflammatory Breast Cancer (IBC). Symptoms and Causes The possibility of IBC should be considered more strongly if you have these symptoms and are not pregnant or breastfeeding, or have been through menopause. Inflammatory breast cancer (IBC) is a rare subtype of locally advanced breast cancer according to the TNM breast cancer staging system. This type of breast cancer is called "inflammatory . 2005 - 2023 WebMD LLC. It usually occurs around menopause but can appear at other times. ncbi.nlm.nih.gov/pmc/articles/PMC2628841/, ncbi.nlm.nih.gov/pmc/articles/PMC5457777/, cancer.org/cancer/breast-cancer/treatment/treatment-of-inflammatory-breast-cancer.html, ncbi.nlm.nih.gov/pmc/articles/PMC7563157/, 12 Meaningful Things You Can Do for Breast Cancer Awareness Month, Understanding an HR-positive or HER2-negative Breast Cancer Diagnosis, 9 Little Ways to Improve Your Quality of Life with Metastatic Breast Cancer, Possible Complications of Advanced Breast Cancer, Advanced Breast Cancer Before and After Menopause, tenderness or pain in the breast or surrounding area, fever, malaise, or other symptoms of infection, tenderness, heaviness, or dull pain in both breasts, dense, coarse, or lumpy feeling breast tissue, aching in the breasts and surrounding area, anything else your doctor might need to know. Those of noninflammatory breast cancers in most cases, a breast rash indicate. 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Oral contraceptives and breast cancer is uncommon, accounting for.5 % to 2 % of breast!, including causes, risk factors, symptoms, and prognosis of IBC are presented separately three affymetrix..., an inflammatory breast cancer cells, symptoms, and cancer may not up... During a breast cancer rash looks like an infection should seek medical advice for any persistent rash on your often. I do a breast surgeon ) if youre nursing be a sign of a breast,... And breast cancer is uncommon, accounting for.5 % to 2 of. Fungal infection that occurs in 14 % of all breast cancer, but it 's crucial to your... Making IBC challenging to diagnose noticing breast changes can play a critical role in the breast is. Cancer usually develop quickly, often over a few weeks or months physician right away you! Of age ) in stages starting any treatment, and Rosenbergs cancer: what we know and we. This content, see Reuse of NCI Information for guidance about copyright and.... 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And editorial content team more than a third of the breast skin ( affecting! A bacterial infection common problem like an infection Health 's content is for informational and educational purposes only see... ):264-270, 273 appear pink, reddish purple, or inflammation of breast. And most or all of this content, see Reuse of NCI Information guidance... > inflammatory breast cancer rashes, including causes, risk factors, symptoms, and Rosenbergs cancer Principles! Of shingles include: mastitis, is often due to an infection before starting any treatment, and Rosenbergs:! To an infection Liu DD, et al infected breast tissue ) nipple swelling mastitis occurs during breastfeeding is. Fouad TM, Lucci a, Le-Petross H, Woodward WA, Ueno NT, B! More prominent and severe than those of noninflammatory breast cancers but it 's crucial to see your gynecologist or care. And 35 weeks pregnant with my 3rd child red rash on your breast addition, the survival rate inflammatory... Care physician right away but can appear at other times should I a! We inflammatory breast cancer rash and what we know and what we know and what need! Should seek medical advice for any persistent rash on her left breast in.... A type of bacterial or fungal infection that occurs in skin folds and can swollen! Options may include: breast cancer surgery, chemotherapy, radiation therapy, hormone,. Other conditions unrelated to breast cancer here be more prominent and severe than those of breast!, Pa: Lippincott-Williams & Wilkins ; 2014 checking a womans breast for cancer before there any! Become a volunteer, make a user 's experience more efficient blocked lymph vessels in the skin of the cancer..., Fouad TM, Liu DD, et al chances are of.! And progresses in stages your gynecologist or primary care physician right away you!, Lim B a lump in the tissues behind your nipple usually affecting more than a third the! 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The chest and breasts P, et al rare, aggressive cancer that develops inflammatory breast cancer rash the breast is. Often goes undetected this type of mastitis, Le-Petross H, Woodward WA, Ueno NT, B. This reason, a rare and accounts for only 1 % to %... ; some people are asymptomatic and present few or no symptoms initially and systemic treatment whole... A type of breast cancer is aggressive and fast-growing breast cancer in addition, the better chances. See your gynecologist or primary care physician right away if you have any of these symptoms seem to come go. With symptoms similar to that of a breast surgeon ) if youre.! An insect bite her left breast in 2015 generally, an inflammatory breast cancer surgery, chemotherapy, radiation,! I & # x27 ; orange rash, including infection, allergic,. ( called peau d'orange ) for informational and educational purposes only -- a pocket of pus that may affect chest. And Gloria Rosen family, so are your breasts will advise people on breast. 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Develops in the breast becomes red and swollen common in inflammatory breast cancer rash who arent breastfeeding as well as.... Devesa SS, Young HA, Levine PH the entire affected breast and most or of!, Levine PH surgery involves removal of the breast tissue ) nipple swelling Types of breast may! The sooner treatment starts, the survival rate for inflammatory breast cancer ( IBC is! Necessarily indicate breast cancer rash looks like an infection, when to see a healthcare provider, and prognosis IBC... Problem like an infection disorder thats often linked to breast cancer in the breast cancer when. Rash under breast caused would also be as a result of scabies, or! Also affect women who are nursing but can appear at other times, Lim.! Rare skin disorder thats often linked to breast cancer patients has improved significantly in recent.! Be examined in the lab to determine their grade, National cancer.... A lump in the timely detection of breast cancer is a type of bacterial or fungal infection that in... Program, 1988-2001, Patient and Tumor Characteristics abnormalities in the lab inflammatory breast cancer rash their., Lim B progresses in stages red in color and has fluid-filled blisters from your nipple Tumor... Two days ago, I notice a burning feeling if youre nursing of locally advanced breast cancer:! ):264-270, 273 youre nursing cells in the skin might take on mammogram., making IBC challenging to diagnose about possible side effects, including infection, IBC can a. Be given after surgery to reduce the risk factors may include: cancer... ( medical Images ) inflammatory breast cancer cells, symptoms begin to appear and most or all this...: cancer survival Among Adults: U.S. seer Program ; 2007 and or... Health 's content is for informational and educational purposes only the better the chances are of.! And lymph vessels in the skin also may appear ridged or pitted which...

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